Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145723 | 0.92 | KDM4E (0.60) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL9153380 | 0.90 | MAPT (0.65) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL9123663 | 0.86 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9125861 | 0.84 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1CASP3 | |
| SCHEMBL9145825 | 0.81 | KDM4E (0.81) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL9148444 | 0.81 | MAPT (0.80) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL8603028 | 0.79 | MAPT (0.78) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL9304337 | 0.78 | MCL1 (0.67) | KMT2AMEN1RAB9ANPC1MAOB | |
| SCHEMBL8652810 | 0.78 | MAPT (0.76) | MAPTKMT2AKDM4ECYP2D6HSD17B10 | |
| SCHEMBL9150983 | 0.77 | FAAH (0.62) | MAPTKMT2AKDM4ECYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476957-A | Dye for heat sensitive recording | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-12-19 | — | — | US | disclosed |