Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689905 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8699900 | 0.87 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL8566204 | 0.87 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10823302 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8564457 | 0.86 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9070334 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8564452 | 0.86 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL10511993 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10618833 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9145601 | 0.85 | KCNH2 (0.69) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | claimed |
| EP-0207420-A2 | Pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | claimed |
| US-5416222-A | Chemical intermediates to prepare pyridinocarboxylic acid derivatives with high antimicrobial activity and excellent pharmacokinetics | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5380874-A | Pyrrolidine carbamates | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5098912-A | Bactericides for grampositive bacteria | DAIICHI SEIYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0207420-A2 | Pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |