Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142418 | 0.90 | KDM4E (0.52) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9144515 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9144111 | 0.87 | TSHR (0.49) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9148326 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9145048 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9144226 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9144038 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9142368 | 0.79 | POLB (0.55) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL9145747 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EUBE2NATMTSHR | |
| SCHEMBL45682 | 0.76 | KDM4E (0.75) | ALDH1A1KDM4EUBE2NATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401756-A | Benzamide platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5304556-A | Platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0548934-A1 | Benzamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |