Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CPN1 | P15169 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059444 | 1.00 | CA12 (0.52) | CA12CA1CA2CA9F2 | |
| SCHEMBL9387897 | 1.00 | CA12 (0.52) | CA12CA1CA2CA9F2 | |
| SCHEMBL9059345 | 0.86 | — | — | |
| SCHEMBL6221404 | 0.86 | — | — | |
| SCHEMBL12668009 | 0.78 | CA12 (0.52) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL4598450 | 0.78 | CA12 (0.52) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL12669685 | 0.78 | CA12 (0.52) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL2080465 | 0.78 | CA12 (0.62) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL3436036 | 0.78 | CA12 (0.62) | CA12CA1CA2CA9SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL4747749 | 0.78 | LMNA (0.39) | CA12CA1CA2CA9F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |