SCHEMBL9147358

SCHEMBL9147358

NC(NCC1CO1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
DPP4 P27487 2/20 0.35
F2 P00734 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35
HTR1A P08908 4/20 0.35
ADRA1D P25100 3/20 0.35
ADRA1A P35348 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185050 0.81 MTOR (0.52) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3670999 0.72 SCN4A (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
Isopropylbenzene SCHEMBL11007534 0.71 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3117376 0.71 TDP1 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
Methane SCHEMBL28528438 0.70 SCN4A (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9321171 0.70 POLB (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4608900 0.69 MEN1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
Aminodiphenylmethane SCHEMBL27672691 0.69 TDP1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL5495958 0.69 TDP1 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8118554 0.69 SIGMAR1 (0.45) DPP4F2CYP3A4MTORRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7082406-A None JP disclosed
JP-H0782406-A PRODUCTION OF RIGID POLYURETHANE FOAM TOHO CHEM IND CO LTD 1995-03-28 JP disclosed
JP-H00782406-A 0001-01-01 JP disclosed