SCHEMBL9147496

SCHEMBL9147496

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149051 0.97
SCHEMBL9149386 0.97 LMNA (0.33) THRBLMNA
SCHEMBL9148413 0.87
SCHEMBL10383360 0.84 LMNA (0.38) THRBLMNA
SCHEMBL10383346 0.84 LMNA (0.38) THRBLMNA
SCHEMBL3313899 0.84 LMNA (0.42) THRBLMNA
SCHEMBL3629816 0.84 LMNA (0.42) THRBLMNA
SCHEMBL11511027 0.84 LMNA (0.42) THRBLMNA
SCHEMBL9137823 0.84 LMNA (0.35) LMNA
SCHEMBL11509926 0.84 LMNA (0.42) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994013612-A1 CHLOROFLUOROETHER COMPOSITIONS AND PREPARATION THEREOF MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-23 WO claimed
US-5420359-A Blood substitutes, solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-30 US disclosed
WO-1994013612-A1 CHLOROFLUOROETHER COMPOSITIONS AND PREPARATION THEREOF MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-23 WO disclosed