Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143114 | 0.90 | PDE4B (0.51) | PDE4BCNR1CNR2MCHR1SCN9A | |
| SCHEMBL3694425 | 0.89 | CETP (0.43) | PDE4BMCHR1SCN9APTGDR2MET | |
| SCHEMBL9141817 | 0.89 | BRD4 (0.41) | PDE4BCNR1CNR2MCHR1PTGDR2 | |
| SCHEMBL41599 | 0.82 | SCN9A (0.47) | PDE4BCNR1CNR2MCHR1SCN9A | |
| SCHEMBL9145008 | 0.76 | PDE4B (0.43) | PDE4BCNR1CNR2MCHR1SCN9A | |
| SCHEMBL675206 | 0.76 | PDE4B (0.44) | PDE4BMCHR1HDAC4TLR9TLR8 | |
| SCHEMBL27390460 | 0.74 | PDE4B (0.46) | PDE4BMCHR1SCN9APTGDR2PRKCZ | |
| SCHEMBL6061977 | 0.74 | PDE4B (0.58) | PDE4BMCHR1SCN9APTGDR2KMT2A | |
| SCHEMBL9142076 | 0.74 | PRKCZ (0.59) | PDE4BMAPTPRKCZKMT2AALDH1A1 | |
| SCHEMBL14218538 | 0.72 | SCN9A (0.45) | PDE4BMCHR1SCN9APTGDR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459262-A | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1995-10-17 | — | — | US | disclosed |
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | disclosed |