SCHEMBL675206

SCHEMBL675206

CCN(C)C(=O)c1ccc(C(F)(F)F)c(-c2ccc(OC)c(OC)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.44
TLR8 Q9NR97 4/20 0.44
TLR7 Q9NYK1 4/20 0.44
TLR9 Q9NR96 3/20 0.44
MCHR1 Q99705 1/20 0.43
HDAC4 P56524 1/20 0.43
PDK2 Q15119 1/20 0.42
ELANE P08246 1/20 0.40
AR P10275 1/20 0.40
GPBAR1 Q8TDU6 1/20 0.39
HTT P42858 1/20 0.39
RORC P51449 1/20 0.39
CYP1A2 P05177 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41599 0.77 SCN9A (0.47) PDE4BMCHR1RORC
SCHEMBL9147697 0.76 PDE4B (0.43) PDE4BTLR8TLR7TLR9MCHR1
SCHEMBL3694425 0.76 CETP (0.43) PDE4BTLR8TLR7TLR9MCHR1
SCHEMBL9145008 0.73 PDE4B (0.43) PDE4BMCHR1HTTHSP90AA1
SCHEMBL1810796 0.71 TTR (0.48) PDE4BHTT
SCHEMBL15656288 0.71 HTT (0.54) PDK2ELANEHTTCYP1A2HSP90AA1
SCHEMBL22451077 0.70 PDE4B (0.83) PDE4B
SCHEMBL24162974 0.69 HSP90AA1 (0.75) HTTCYP1A2HSP90AA1HSP90AB1BLM
SCHEMBL6061977 0.69 PDE4B (0.58) PDE4BMCHR1
SCHEMBL15652837 0.68 CYP1A2 (0.52) ELANEHTTCYP1A2HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 US disclosed
US-10899932-B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles BASF SE (DE) 2021-01-26 US disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 US disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 EP disclosed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 EP disclosed
EP-3498098-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2019-06-19 EP disclosed
US-20180334569-A9 NON-AMPHOTERIC, QUATERNISABLE AND WATER-SOLUBLE POLYMERS FOR MODIFYING THE SURFACE CHARGE OF SOLID PARTICLES BASF SE (DE) 2018-11-22 US disclosed
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-10-18 US disclosed
EP-3378313-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-09-26 EP disclosed
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups BASF SE (DE) 2018-07-10 US disclosed
US-20080188530-A1 Synergistic combination of a Strobilurin derivative, a carboxamides and and a biphenyl joined to a substituted thiazole through an amide BASF AKTIENGESELLSCHAFT (DE) 2008-08-07 US disclosed
US-20080153701-A1 Fungicidal Mixtures BASF AKTIENGESELLSCHAFT (DE) 2008-06-26 US disclosed
WO-2008071714-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE ROHM AND HAAS COMPANY (US) 2008-06-19 WO disclosed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO disclosed
US-20080064597-A1 Fungicidal Mixtures BASF AKTIENGESELLSCHAFT (DE) 2008-03-13 US disclosed
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens BASF AKTIENGESELLSCHAFT (DE) 2008-02-21 US disclosed
US-20080039319-A1 Fungicidal Mixtures and Novel Triazolopyrimidines BASF AKTIENGESELLSCHAFT (DE) 2008-02-14 US disclosed
US-20080039320-A1 Use Of Menadione BASF AKTIENGESELLSCHAFT (DE) 2008-02-14 US disclosed
WO-2007122264-A2 COMPOSITION COMPRISING A GLUCAN OR A GLUCAN DERIVATIVE AND A PESTICIDE AND METHODS FOR IMPROVING PLANT HEALTH BASF SE (DE) 2007-11-01 WO disclosed
EP-1849364-A1 Composition comprising a glucan or a glucan derivative and a pesticide and methods for improving plant health BASF AKTIENGESELLSCHAFT (DE) 2007-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064597-A1 Fungicidal Mixtures ARSA, NAT1, DDT PDE4B 4490/4885TLR8 3876/4885TLR7 2743/4885
US-20080039320-A1 Use Of Menadione MANBA, MGAM2, MGAM PDE4B 1704/4885TLR8 3971/4885TLR7 4578/4885
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A PDE4B 827/4885TLR8 783/4885TLR7 95/4885
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS PUF60, POLR1C, PICALM PDE4B 3617/4885TLR8 3372/4885TLR7 2690/4885
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups PUF60, POLR1C, PICALM PDE4B 3617/4885TLR8 3372/4885TLR7 2690/4885
US-20080153701-A1 Fungicidal Mixtures STS, DDT, CYP4X1 PDE4B 892/4885TLR8 3680/4885TLR7 2403/4885
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens DDT, CYP4X1, STS PDE4B 538/4885TLR8 4143/4885TLR7 3470/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 PDE4B 327/4885TLR8 3986/4885TLR7 3563/4885
US-20080039319-A1 Fungicidal Mixtures and Novel Triazolopyrimidines ATIC, ARSA, AOC1 PDE4B 2980/4885TLR8 3317/4885TLR7 969/4885
US-20080188530-A1 Synergistic combination of a Strobilurin derivative, a carboxamides and and a biphenyl joined to a substituted thiazole through an amide SUCLG1, ARSA, STS PDE4B 4570/4885TLR8 3104/4885TLR7 3048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.