Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 6/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147858 | 1.00 | LMNA (0.52) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9148662 | 0.91 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9148668 | 0.91 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9215206 | 0.88 | LMNA (0.41) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9144116 | 0.83 | DPP4 (0.47) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9146376 | 0.83 | DPP4 (0.65) | LMNADPP4EPHA2FLT4GSK3B | |
| SCHEMBL9146813 | 0.83 | DPP4 (0.65) | LMNADPP4EPHA2FLT4GSK3B | |
| SCHEMBL9146820 | 0.83 | DPP4 (0.65) | LMNADPP4EPHA2FLT4GSK3B | |
| SCHEMBL9144124 | 0.83 | DPP4 (0.47) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9147443 | 0.81 | EPHA2 (0.57) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388298-B1 | Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines | ESTEVE LABOR DR (ES) | 1995-06-21 | — | — | EP | claimed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | claimed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | disclosed |