Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940560 | 0.89 | KCNH2 (0.49) | KCNH2GSK3BTDP1KDM4EALDH1A1 | |
| SCHEMBL6218398 | 0.88 | KCNH2 (0.49) | ADRB2KCNH2GSK3BTDP1KDM4E | |
| SCHEMBL9148042 | 0.88 | ADRB2 (0.55) | ADRB2KCNH2TDP1KDM4EALDH1A1 | |
| SCHEMBL6783818 | 0.88 | ADRB2 (0.59) | ADRB2KCNH2TDP1KDM4EALDH1A1 | |
| SCHEMBL2080448 | 0.88 | CYP3A4 (0.49) | ADRB2KCNH2GSK3BTDP1KDM4E | |
| SCHEMBL2080449 | 0.88 | CYP3A4 (0.49) | ADRB2KCNH2GSK3BTDP1KDM4E | |
| SCHEMBL7496082 | 0.87 | KCNH2 (0.48) | ADRB2KCNH2GSK3BTDP1KDM4E | |
| SCHEMBL115123 | 0.87 | ADRB2 (0.54) | ADRB2KCNH2TDP1KDM4EALDH1A1 | |
| SCHEMBL1989474 | 0.86 | ADRB2 (0.61) | ADRB2KCNH2GSK3BTDP1KDM4E | |
| SCHEMBL29391687 | 0.86 | ADRB2 (0.61) | ADRB2KCNH2GSK3BTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143016-A | Synthesis process of 1-cyclopropyl-7-fluoro-8-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid | 奥盖尼克材料(苏州)有限公司 | 2023-12-01 | — | — | CN | claimed |
| US-6329391-B1 | ANTIBIOTICS, BACTERICIDES USING QUINOLONES | THE PROCTER & GAMBLE CO. | 2001-12-11 | — | — | US | claimed |
| CN-117143016-A | Synthesis process of 1-cyclopropyl-7-fluoro-8-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid | 奥盖尼克材料(苏州)有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-8158798-B2 | Coupling process for preparing quinolone intermediates | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-04-17 | — | — | US | disclosed |
| US-8158798-B2 | Coupling process for preparing quinolone intermediates | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-04-17 | — | — | US | disclosed |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-8039485-B2 | Malate salts, and polymorphs of (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid | WARNER CHILCOTT COMPANY, LLC (US) | 2011-10-18 | — | — | US | disclosed |
| US-8039485-B2 | Malate salts, and polymorphs of (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid | WARNER CHILCOTT COMPANY, LLC (US) | 2011-10-18 | — | — | US | disclosed |
| EP-2256120-A1 | Oxazolidinone-quinolone hybrids as antibacterial compounds | Actelion Pharmaceuticals Ltd. (CH) | 2010-12-01 | — | — | EP | disclosed |
| US-20070232650-A1 | Malate salts, and polymorphs of (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid | THE PROCTER & GAMBLE COMPANY | 2007-10-04 | — | — | US | disclosed |
| WO-2007110835-A2 | A COUPLING PROCESS FOR PREPARING QUINOLONE INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070232804-A1 | Coupling process for preparing quinolone intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-04 | — | — | US | disclosed |
| US-20060100436-A1 | Antimicrobial quinolones, their compositions, and uses | WARNER CHILCOTT COMPANY, LLC | 2006-05-11 | — | — | US | disclosed |
| EP-1532114-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6803469-B2 | CYCLIZING IN THE PRESENCE OF A SILYLATING AGENT | THE PROCTER & GAMBLE COMPANY | 2004-10-12 | — | — | US | disclosed |
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | WARNER CHILCOTT COMPANY, LLC | 2004-04-01 | — | — | US | disclosed |
| WO-2004013103-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |
| US-6329391-B1 | ANTIBIOTICS, BACTERICIDES USING QUINOLONES | THE PROCTER & GAMBLE CO. | 2001-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100436-A1 | Antimicrobial quinolones, their compositions, and uses | Q6ZSR9, RECQL, QARS1 | ADRB2 2703/4885KCNH2 1112/4885GSK3B 3108/4885 |
| US-20070232804-A1 | Coupling process for preparing quinolone intermediates | CYP3A4, CYP4B1, CYP4X1 | ADRB2 2269/4885KCNH2 1111/4885GSK3B 3457/4885 |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | ADRB2 702/4885KCNH2 1477/4885GSK3B 3846/4885 |
| US-20070232650-A1 | Malate salts, and polymorphs of (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid | SLC25A11, MDH2, MDH1 | ADRB2 3221/4885KCNH2 2469/4885GSK3B 3708/4885 |
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | QPCT, CCNT1, TOP1 | ADRB2 1089/4885KCNH2 665/4885GSK3B 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.