Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146250 | 0.83 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8393547 | 0.82 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9148295 | 0.81 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL9148183 | 0.81 | CTSK (0.43) | CTSKCTSS | |
| SCHEMBL1134628 | 0.77 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL22731080 | 0.77 | CA1 (0.63) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8393549 | 0.76 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9148279 | 0.76 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7399188 | 0.76 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7503388 | 0.76 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395958-A | Intermediates for enzyme inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0590650-A1 | Cyclopropene derivatives with thiol protease inhibiting activity | Mitsubishi Chemical Corporation (JP) | 1994-04-06 | — | — | EP | disclosed |