Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424828 | 0.86 | CYP3A4 (0.44) | HRH4HRH2NAMPTALDH1A1CYP3A4 | |
| SCHEMBL9147554 | 0.84 | HRH4 (0.43) | HRH4HRH2NAMPTALDH1A1CYP3A4 | |
| SCHEMBL8620022 | 0.80 | HRH4 (0.40) | HRH4HRH2NAMPTALDH1A1CYP3A4 | |
| SCHEMBL9147482 | 0.79 | BCL6 (0.53) | HRH4HRH2NAMPTALDH1A1CYP3A4 | |
| SCHEMBL9148294 | 0.79 | HRH4 (0.50) | HRH4HRH2NAMPT | |
| SCHEMBL7349710 | 0.75 | QPCT (0.37) | ALDH1A1NPC1RAB9ALMNAGAA | |
| SCHEMBL7349695 | 0.75 | QPCT (0.37) | ALDH1A1NPC1RAB9ALMNAGAA | |
| SCHEMBL7349700 | 0.75 | QPCT (0.37) | ALDH1A1NPC1RAB9ALMNAGAA | |
| SCHEMBL7353949 | 0.74 | HRH4 (0.42) | HRH4HRH2ROCK2KMT2AKDM4E | |
| SCHEMBL7430606 | 0.74 | POLB (0.53) | HRH4HRH2SMN1; SMN2ROCK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655057-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS. | UPJOHN CO (US) | 1995-05-31 | — | — | EP | disclosed |