Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627824 | 0.76 | AGTR2 (0.56) | AGTR2 | |
| SCHEMBL3631709 | 0.76 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9031922 | 0.75 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9141157 | 0.72 | AGTR1 (0.67) | AGTR1 | |
| SCHEMBL647 | 0.71 | — | — | |
| SCHEMBL1258786 | 0.70 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL1258665 | 0.70 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL1257529 | 0.70 | AGTR2 (0.47) | AGTR2 | |
| SCHEMBL1257795 | 0.70 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9166785 | 0.70 | AGTR1 (1.00) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |