Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266718 | 0.89 | THRB (0.48) | MAPTSMN1; SMN2THRBTHRABCHE | |
| SCHEMBL11261251 | 0.88 | THRB (0.50) | MAPTSMN1; SMN2THRBTHRABCHE | |
| SCHEMBL11265379 | 0.83 | THRB (0.44) | MAPTSMN1; SMN2THRBTHRABCHE | |
| SCHEMBL11469321 | 0.83 | THRB (0.44) | MAPTSMN1; SMN2THRBTHRABCHE | |
| SCHEMBL11459835 | 0.82 | THRB (0.47) | MAPTSMN1; SMN2THRBTHRABCHE | |
| SCHEMBL9148006 | 0.81 | SPHK1 (0.41) | MAPTSMN1; SMN2THRBTHRALMNA | |
| SCHEMBL9144799 | 0.80 | SPHK1 (0.42) | MAPTSMN1; SMN2THRBTHRACYP2C9 | |
| SCHEMBL9145915 | 0.78 | MAPT (0.40) | MAPTSMN1; SMN2THRBTHRATP53 | |
| SCHEMBL9144866 | 0.76 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2NPC1LMNACYP1A2 | |
| SCHEMBL9145092 | 0.76 | KMT2A (0.44) | MAPTSMN1; SMN2PPARAPPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399290-A | Liquid crystals with (polysila) alkyl wing groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1995-03-21 | — | — | US | disclosed |