Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.56 |
| ▸ | BRS3 | P32247 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154033 | 0.93 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9842172 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2BRS3 | |
| SCHEMBL9842316 | 0.90 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9150286 | 0.89 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9154711 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9152688 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9149242 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9157099 | 0.85 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9842177 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9154093 | 0.83 | AGTR1 (0.52) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389659-A | Hypotensive agents | GLAXO GROUP LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| WO-1993005025-A1 | C-LINKED PYRAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-03-18 | — | — | WO | disclosed |
| EP-0446062-A1 | C-Linked pyrazole derivatives | GLAXO GROUP LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |