Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416478 | 0.89 | TDP1 (0.32) | TDP1KCNH2 | |
| SCHEMBL9146529 | 0.86 | LMNA (0.37) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL7849723 | 0.84 | LMNA (0.41) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9149179 | 0.83 | CYP3A4 (0.47) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9146597 | 0.83 | CYP3A4 (0.47) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9146602 | 0.83 | CYP3A4 (0.47) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9149043 | 0.81 | EPHA2 (0.52) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9145431 | 0.76 | KCNH2 (0.47) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL8783289 | 0.76 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL7849348 | 0.76 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |