Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149218 | 1.00 | HDAC8 (0.44) | HDAC8HDAC1ALDH1A1LMNAGAA | |
| SCHEMBL9151555 | 0.87 | HDAC1 (0.37) | HDAC8HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9151561 | 0.87 | HDAC1 (0.37) | HDAC8HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9150366 | 0.84 | ALDH1A1 (0.44) | HDAC8HDAC1ALDH1A1GAA | |
| SCHEMBL9147568 | 0.84 | ALDH1A1 (0.44) | HDAC8HDAC1ALDH1A1GAA | |
| SCHEMBL9151342 | 0.83 | HDAC8 (0.50) | HDAC8HDAC1ALDH1A1LMNAGAA | |
| SCHEMBL9147770 | 0.78 | CNR2 (0.48) | HDAC8HDAC1ALDH1A1LMNAGAA | |
| SCHEMBL2528789 | 0.76 | HDAC8 (0.45) | HDAC8HDAC1ALDH1A1LMNAGAA | |
| SCHEMBL6539670 | 0.69 | ALDH1A1 (0.49) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6205477 | 0.68 | HDAC3 (0.55) | HDAC1ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |