SCHEMBL9150366

SCHEMBL9150366

CC(C#N)CCCCCC(=O)N[C@H](C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
ASAH1 Q13510 2/20 0.44
ACER2 Q5QJU3 1/20 0.44
CERT1 Q9Y5P4 3/20 0.39
MAPT P10636 1/20 0.38
HDAC8 Q9BY41 4/20 0.37
HDAC1 Q13547 3/20 0.37
HPGD P15428 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
GAA P10253 1/20 0.37
SMPD2 O60906 1/20 0.37
SMPD1 P17405 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147568 1.00 ALDH1A1 (0.44) ALDH1A1ASAH1ACER2CERT1MAPT
SCHEMBL9151561 0.86 HDAC1 (0.37) ALDH1A1ASAH1ACER2HDAC8HDAC1
SCHEMBL9151555 0.86 HDAC1 (0.37) ALDH1A1ASAH1ACER2HDAC8HDAC1
SCHEMBL9149218 0.84 HDAC8 (0.44) ALDH1A1HDAC8HDAC1GAA
SCHEMBL9149208 0.84 HDAC8 (0.44) ALDH1A1HDAC8HDAC1GAA
SCHEMBL9150499 0.80 ASAH1 (0.46) ALDH1A1ASAH1ACER2CERT1MAPT
SCHEMBL11717912 0.73 TDP1 (0.44) ALDH1A1MAPTCYP1A2CYP3A4TSHR
SCHEMBL11720911 0.72 UBE2N (0.45) ALDH1A1MAPTCYP1A2CYP3A4TSHR
Hydrochloric Acid SCHEMBL11721855 0.71 UBE2N (0.47) ALDH1A1MAPTCYP1A2CYP3A4TSHR
SCHEMBL11717078 0.70 ALDH1A1 (0.54) ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403852-A Antiinflammatory agents LABORATOIRE ROGER BELLON (FR) 1995-04-04 US disclosed