SCHEMBL9149293

SCHEMBL9149293

Nc1nc(=O)n([C@@H]2CC(O)[C@H](CO)S2)cc1F

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.53
DCK P27707 12/20 0.39
POLG P54098 1/20 0.38
ADRB1 P08588 1/20 0.36
DNMT1 P26358 1/20 0.36
AHCY P23526 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036187 1.00 ALB (0.53) ALBDCKPOLGADRB1DNMT1
SCHEMBL6306806 0.89 ALB (0.52) ALBDCKPOLG
SCHEMBL6303823 0.89 ALB (0.52) ALBDCKPOLG
SCHEMBL12642437 0.85 ALB (0.37) ALBADRB1DNMT1LMNA
SCHEMBL8997837 0.80 TK1 (0.40) ALBADRB1DNMT1LMNA
SCHEMBL2640083 0.80 TK1 (0.40) ALBADRB1DNMT1LMNA
SCHEMBL1956184 0.80 ALB (0.52) ALBDCKPOLGDNMT1LMNA
SCHEMBL1956182 0.80 ALB (0.52) ALBDCKPOLGDNMT1LMNA
SCHEMBL12162839 0.80 ALB (0.52) ALBDCKPOLGDNMT1LMNA
SCHEMBL599407 0.79 ALB (0.56) ALBDCKPOLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0658166-A1 ANTIVIRAL PYRIMIDINE NUCLEOSIDES THE UNIVERSITY OF BIRMINGHAM (GB) 1995-06-21 EP disclosed
WO-1994005687-A1 ANTIVIRAL PYRIMIDINE NUCLEOSIDES UNIVERSITY OF BIRMINGHAM (GB) 1994-03-17 WO disclosed