Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 3/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640083 | 1.00 | TK1 (0.40) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL2036187 | 0.80 | ALB (0.53) | ALBDNMT1ADRB1LMNA | |
| SCHEMBL9149293 | 0.80 | ALB (0.53) | ALBDNMT1ADRB1LMNA | |
| SCHEMBL12642437 | 0.80 | ALB (0.37) | BLMPMP22ALBDNMT1ADRB1 | |
| SCHEMBL445633 | 0.77 | TK1 (0.64) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL2639023 | 0.77 | TK1 (0.64) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL445632 | 0.77 | TK1 (0.64) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL2584404 | 0.77 | TK1 (0.43) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL2584408 | 0.77 | TK1 (0.43) | TK1BLMPMP22CYP1A2CYP3A4 | |
| SCHEMBL6359874 | 0.77 | TK1 (0.64) | TK1BLMPMP22CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521163-A | TREATMENT OF HERPES VIRUS WITH 1'-DEOXY-5-ETHYL-4'-THIO-BETA URIDINE | UNIVERSITY OF BIRMINGHAM (GB) | 1996-05-28 | — | — | US | disclosed |
| US-5356882-A | Treating herpes virus | UNIVERSITY OF BIRMINGHAM (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | disclosed |
| EP-0409575-A1 | Antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-01-23 | — | — | EP | disclosed |