Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16593006 | 0.91 | CSNK2A1 (0.49) | PTPN11THRATHRBATMHPGD | |
| SCHEMBL9437162 | 0.90 | PTPN11 (0.74) | PTPN11THRATHRBRARBPTPN1 | |
| SCHEMBL9626774 | 0.90 | PTPN11 (0.74) | PTPN11THRATHRBRARBPTPN1 | |
| SCHEMBL9437159 | 0.90 | PTPN11 (0.60) | PTPN11THRATHRBRARBPTPN1 | |
| SCHEMBL9399929 | 0.86 | THRA (0.53) | PTPN11THRATHRBPTPN1PTPN6 | |
| SCHEMBL9398890 | 0.86 | THRA (0.53) | PTPN11THRATHRBPTPN1PTPN6 | |
| SCHEMBL9145276 | 0.85 | CREBBP (0.55) | ALDH1A1GAA | |
| SCHEMBL9154559 | 0.84 | PTPN11 (0.60) | PTPN11THRATHRBRARBPTPN1 | |
| SCHEMBL10338888 | 0.84 | PTPN11 (0.54) | PTPN11THRATHRBRARBPTPN1 | |
| SCHEMBL5339778 | 0.84 | PTPN11 (0.66) | PTPN11THRATHRBRARBS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |