SCHEMBL9145276

SCHEMBL9145276

CCOc1ccc(-c2ccc(C(C)=O)cc2)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 1/20 0.55
RORC P51449 1/20 0.55
ERN1 O75460 1/20 0.51
POLB P06746 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
MCL1 Q07820 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 3/20 0.49
MAPT P10636 3/20 0.49
KDM4E B2RXH2 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B1 P14061 1/20 0.49
MAPK1 P28482 1/20 0.48
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16593006 0.88 CSNK2A1 (0.49) CREBBPRORCMAPTHSD17B1NPC1
SCHEMBL5347979 0.88 MEN1 (0.60) RORCERN1POLBMEN1LMNA
SCHEMBL8204769 0.87 CREBBP (0.66) CREBBPRORCPOLBMEN1LMNA
SCHEMBL9149334 0.85 PTPN11 (0.60) GAAALDH1A1
SCHEMBL9144904 0.84 CYP3A4 (0.44) CREBBPRORCERN1POLBLMNA
SCHEMBL9146265 0.81 HPGD (0.41) MAPTNPSR1HSD17B1NPC1RAB9A
SCHEMBL30837251 0.78 KMO (0.51) MAPTHSD17B1SMN1; SMN2
SCHEMBL2964617 0.78 CREBBP (0.61) CREBBPRORCMEN1LMNAKMT2A
SCHEMBL11808755 0.78 POLB (0.58) CREBBPRORCPOLBMEN1LMNA
SCHEMBL566498 0.78 POLB (0.70) RORCPOLBMEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397504-A Liquid crystal KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-03-14 US disclosed
EP-0315701-B1 BIPHENYL COMPOUND KANTO KAGAKU (JP) 1993-12-29 EP disclosed
EP-0315701-A1 BIPHENYL COMPOUND KANTO KAGAKU KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed