Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001396 | 0.86 | HTT (0.36) | SMN1; SMN2HTTNPC1L3MBTL1MAPT | |
| SCHEMBL9579969 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2NPC1EPHX1MEN1KMT2A | |
| SCHEMBL27422878 | 0.82 | HTT (0.33) | HTTNPC1L3MBTL1MAPTALOX15 | |
| SCHEMBL9001399 | 0.78 | CES1 (0.34) | SMN1; SMN2HTTNPC1L3MBTL1MAPT | |
| SCHEMBL6101719 | 0.78 | EP300 (0.33) | HTTNPC1L3MBTL1MAPTALOX15 | |
| SCHEMBL27335677 | 0.77 | CES1 (0.33) | SMN1; SMN2HTTNPC1L3MBTL1MAPT | |
| SCHEMBL9001403 | 0.77 | CES1 (0.39) | HTTL3MBTL1MAPTALOX15HBB | |
| SCHEMBL29067489 | 0.75 | NPC1 (0.41) | SMN1; SMN2HTTNPC1L3MBTL1MAPT | |
| SCHEMBL28386645 | 0.71 | ALDH1A1 (0.34) | HTTNPC1L3MBTL1MAPTALOX15 | |
| SCHEMBL27335678 | 0.71 | NPC1 (0.37) | SMN1; SMN2NPC1EP300MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629217-A4 | RIGID-ROD POLYMERS. | MAXDEM INC (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0629217-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993018076-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1993-09-16 | — | — | WO | disclosed |