Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152339 | 1.00 | NPSR1 (0.38) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9149471 | 1.00 | NPSR1 (0.38) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9149464 | 1.00 | NPSR1 (0.38) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9152365 | 0.90 | CES2 (0.40) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9152369 | 0.90 | CES2 (0.40) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9152357 | 0.90 | CES2 (0.40) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13483594 | 0.87 | MAPT (0.35) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8159367 | 0.87 | NPSR1 (0.39) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4464758 | 0.87 | NPSR1 (0.39) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23298400 | 0.86 | MAPT (0.36) | NPSR1GAAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |