Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.51 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.51 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.44 |
| ▸ | CDC25B | P30305 | 5/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149963 | 1.00 | GJB2 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7770650 | 1.00 | GJB2 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7770653 | 1.00 | GJB2 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7563593 | 0.96 | SSTR1 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL264661 | 0.96 | SSTR1 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7564133 | 0.95 | SSTR1 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7564138 | 0.95 | SSTR1 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14571365 | 0.93 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2562480 | 0.93 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL1561732 | 0.93 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474986-A | Galabiose derivatives modified at 3* and anomeric positions | SYMBICOM AKTIEBOLAG (SE) | 1995-12-12 | — | — | US | disclosed |
| EP-0428605-B1 | SYNTHETIC RECEPTOR ANALOGUES | SYMBICOM AB (SE) | 1994-10-19 | — | — | EP | disclosed |