Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079305 | 0.78 | CYP3A4 (0.51) | LSSNPC1KDM4EGABRA5CYP3A4 | |
| SCHEMBL9699977 | 0.78 | CYP3A4 (0.51) | LSSNPC1KDM4EGABRA5CYP3A4 | |
| SCHEMBL7564821 | 0.78 | CYP3A4 (0.51) | LSSNPC1KDM4EGABRA5CYP3A4 | |
| SCHEMBL7332235 | 0.78 | CYP3A4 (0.51) | LSSNPC1KDM4EGABRA5CYP3A4 | |
| SCHEMBL7882592 | 0.78 | CYP3A4 (0.51) | LSSNPC1KDM4EGABRA5CYP3A4 | |
| SCHEMBL9156201 | 0.78 | LPAR3 (0.41) | LSSNPC1LPAR3ALDH1A1HPGD | |
| SCHEMBL30993068 | 0.78 | LSS (0.40) | LSSALDH1A1KDM4EGABRA5CYP3A4 | |
| SCHEMBL3994090 | 0.76 | CYP3A4 (0.49) | LSSNPC1KDM4EGABRA5L3MBTL1 | |
| SCHEMBL30993903 | 0.76 | LOX (0.41) | LSSALDH1A1KDM4EGABRA5CYP3A4 | |
| SCHEMBL11338748 | 0.76 | L3MBTL1 (0.51) | LSSALDH1A1TDP1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |