Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 6/20 | 0.33 |
| ▸ | EDNRA | P25101 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150109 | 0.78 | LSS (0.47) | LPAR3LPAR2CDK1CCNB1CCNA2 | |
| SCHEMBL18009502 | 0.75 | MAPK1 (0.38) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL9866752 | 0.74 | SLC2A1 (0.33) | LPAR3LPAR2CDK1CCNB1CCNA2 | |
| SCHEMBL9544988 | 0.74 | MEN1 (0.42) | LPAR3LPAR2CDK1CCNB1CCNA2 | |
| SCHEMBL9299546 | 0.73 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1LSSTDP1 | |
| SCHEMBL11338748 | 0.73 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1LSSTDP1 | |
| SCHEMBL29566876 | 0.71 | ALDH1A1 (0.41) | LPAR3LPAR2CDK1CCNB1CCNA2 | |
| SCHEMBL9506242 | 0.70 | RARB (0.47) | NPC1TSHRALDH1A1L3MBTL1HPGD | |
| SCHEMBL15005037 | 0.70 | ALDH1A1 (0.43) | LPAR3LPAR2CDK1CCNB1CCNA2 | |
| SCHEMBL17003487 | 0.69 | EDNRA (0.37) | EDNRBEDNRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |