Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884545 | 0.93 | KDM4E (0.52) | RXRBRXRAKDM4EGAAALDH1A1 | |
| SCHEMBL9149082 | 0.92 | MCL1 (0.53) | RXRBRXRARARBMCL1PDE4A | |
| SCHEMBL14084580 | 0.88 | EGFR (0.56) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL2811988 | 0.87 | RXRB (0.63) | RXRBRXRARARBMCL1PDE4A | |
| SCHEMBL1498034 | 0.87 | RXRB (0.70) | RXRBRXRARARBMCL1PDE4A | |
| SCHEMBL29771992 | 0.87 | RXRB (0.70) | RXRBRXRARARBMCL1PDE4A | |
| SCHEMBL9149067 | 0.86 | KDM4E (0.46) | RXRBRXRAMCL1KDM4EGAA | |
| SCHEMBL15136227 | 0.85 | MCL1 (0.61) | RXRBRXRARARBMCL1KDM4E | |
| Hydrochloric Acid SCHEMBL4365452 | 0.85 | RXRB (0.68) | RXRBRXRARARBMCL1PDE4A | |
| Hydrochloric Acid SCHEMBL9150803 | 0.85 | RXRB (0.68) | RXRBRXRARARBMCL1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439616-B1 | METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS | UBE INDUSTRIES (JP) | 1995-01-04 | — | — | EP | disclosed |