Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157976 | 0.92 | MCL1 (0.53) | MCL1RXRBRXRAKDM4ECFD | |
| SCHEMBL9149067 | 0.92 | KDM4E (0.46) | MCL1RXRBRXRAKDM4EALDH1A1 | |
| SCHEMBL9150203 | 0.92 | RXRB (0.57) | MCL1RXRBRXRARARBPDE4A | |
| SCHEMBL70184 | 0.88 | KDM4E (0.47) | MCL1KDM4EALDH1A1GLAGAA | |
| SCHEMBL15136227 | 0.87 | MCL1 (0.61) | MCL1RXRBRXRARARBKDM4E | |
| SCHEMBL9154339 | 0.86 | MCL1 (0.62) | MCL1RXRBRXRARARBPDE4A | |
| Hydrochloric Acid SCHEMBL9154099 | 0.84 | MCL1 (0.61) | MCL1RXRBRXRARARBPDE4A | |
| SCHEMBL2884545 | 0.84 | KDM4E (0.52) | RXRBRXRAKDM4EALDH1A1GLA | |
| SCHEMBL7671667 | 0.83 | NR4A2 (0.56) | MCL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL13941279 | 0.83 | CFD (0.50) | MCL1KDM4ECFDALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439616-B1 | METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS | UBE INDUSTRIES (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5243067-A | Oxidative coupling | UBE INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0439616-A1 | METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS | UBE INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |