Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.60 |
| ▸ | TOP2A | P11388 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CBS | P35520 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929736 | 0.86 | TDP1 (0.60) | PTGESTOP2APTPN1TDP1L3MBTL1 | |
| SCHEMBL8400549 | 0.84 | PTPN1 (0.66) | PTGESTOP2APTPN1TDP1L3MBTL1 | |
| SCHEMBL8402307 | 0.84 | PTPN1 (0.66) | PTGESTOP2APTPN1TDP1L3MBTL1 | |
| SCHEMBL8750720 | 0.83 | PTGES (0.66) | PTGESTOP2APTPN1TDP1L3MBTL1 | |
| SCHEMBL29979434 | 0.83 | PTGES (0.66) | PTGESTOP2APTPN1TDP1L3MBTL1 | |
| SCHEMBL9741945 | 0.80 | TDP1 (0.62) | TDP1L3MBTL1CBSALDH1A1TSHR | |
| SCHEMBL29683894 | 0.79 | PTGES (0.67) | PTGESTOP2APTPN1TDP1CYP3A4 | |
| SCHEMBL2762730 | 0.79 | PTGES (0.67) | PTGESTOP2APTPN1TDP1CYP3A4 | |
| SCHEMBL24511794 | 0.79 | PTPN1 (0.76) | PTGESTOP2APTPN1TDP1CYP3A4 | |
| SCHEMBL34463357 | 0.79 | PTPN1 (0.76) | PTGESTOP2APTPN1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386019-A | Reacting a sugar glycal with a 2,4-dihydroxybenzoic acid derivative, and combining the aryl glycoside formed with a suitable aryl compound | YALE UNIVERSITY (US) | 1995-01-31 | — | — | US | claimed |
| WO-1993014099-A1 | SYNTHESIS OF INHIBITORS OF CALMODULIN-MEDIATED ENZYMES | YALE UNIVERSITY (US) | 1993-07-22 | — | — | WO | claimed |
| US-5386019-A | Reacting a sugar glycal with a 2,4-dihydroxybenzoic acid derivative, and combining the aryl glycoside formed with a suitable aryl compound | YALE UNIVERSITY (US) | 1995-01-31 | — | — | US | disclosed |
| WO-1993014099-A1 | SYNTHESIS OF INHIBITORS OF CALMODULIN-MEDIATED ENZYMES | YALE UNIVERSITY (US) | 1993-07-22 | — | — | WO | disclosed |