Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291138 | 1.00 | CNR1 (0.56) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL21413172 | 1.00 | CNR1 (0.56) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL22748618 | 0.88 | PLA2G4A (0.50) | CNR1PLA2G4ATP53TSHRRARB | |
| SCHEMBL7755595 | 0.86 | KDM5A (0.48) | CNR1PLA2G4APOLBKDM4EALDH1A1 | |
| SCHEMBL28669934 | 0.85 | CNR1 (0.54) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL29038550 | 0.85 | CNR1 (0.54) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL29038572 | 0.85 | CNR1 (0.54) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL27945337 | 0.85 | CNR1 (0.54) | CNR1PLA2G4ANPC1RAB9AHTT | |
| SCHEMBL22749024 | 0.85 | PLA2G4A (0.47) | CNR1PLA2G4APOLBMAPTALDH1A1 | |
| SCHEMBL22748665 | 0.85 | PLA2G4A (0.50) | CNR1PLA2G4ATP53TSHRRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |