Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21413172 | 0.86 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1KDM4EPOLB | |
| SCHEMBL9150323 | 0.86 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1KDM4EPOLB | |
| SCHEMBL22291138 | 0.86 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1KDM4EPOLB | |
| SCHEMBL15098118 | 0.85 | CNR1 (0.43) | KDM5AKDM5BL3MBTL1PLA2G4ACNR1 | |
| SCHEMBL29132913 | 0.84 | PLA2G4A (0.43) | KDM5AKDM5BL3MBTL1PLA2G4ACNR1 | |
| SCHEMBL969727 | 0.84 | AKR1B1 (0.46) | KDM5AKDM5BL3MBTL1PLA2G4ACNR1 | |
| SCHEMBL29132872 | 0.82 | CNR1 (0.46) | KDM5AKDM5BL3MBTL1PLA2G4ACNR1 | |
| SCHEMBL26134331 | 0.81 | AKR1B1 (0.43) | L3MBTL1PLA2G4ACNR1AKR1B1ALDH1A1 | |
| SCHEMBL22063999 | 0.80 | ALDH1A1 (0.47) | PLA2G4AAKR1B1ALDH1A1HCAR3 | |
| SCHEMBL22748618 | 0.78 | PLA2G4A (0.50) | PLA2G4ACNR1RARBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154519-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-1071427-A1 | INTERMITTENT CLAUDICATION THERAPEUTIC DRUGS COMPRISING PYRROLOAZEPINES | SUNTORY LIMITED (JP) | 2001-01-31 | — | — | EP | disclosed |
| WO-2000048602-A1 | INTERMITTENT CLAUDICATION THERAPEUTIC DRUGS COMPRISING PYRROLOAZEPINES | SUNTORY LIMITED (JP) | 2000-08-24 | — | — | WO | disclosed |