Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156108 | 0.83 | — | — | |
| SCHEMBL25253103 | 0.83 | — | — | |
| SCHEMBL10712195 | 0.78 | HSD17B10 (0.36) | PDE4ACYP1A2CYP2C19 | |
| SCHEMBL9079382 | 0.77 | — | — | |
| SCHEMBL9188618 | 0.75 | LMNA (0.34) | PDE4ACYP1A2CYP2C19PDE4BPDE4C | |
| SCHEMBL2494240 | 0.74 | TSHR (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9151003 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL10711352 | 0.71 | PDE4A (0.42) | PDE4ACYP1A2CYP2C19PDE4BPDE4C | |
| SCHEMBL9155654 | 0.71 | MAPK1 (0.42) | PDE4ACYP1A2CYP2C19PDE4BPDE4C | |
| SCHEMBL9190006 | 0.69 | MEN1 (0.36) | PDE4ACYP1A2CYP2C19PDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482477-B1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazines | BASF AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-5130428-A | Reacting trichloroacetamidinoguanidines with trifluoracetic acid derivatives and then with an alcohol or thiol | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0482477-A1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazines | BASF Aktiengesellschaft (DE) | 1992-04-29 | — | — | EP | disclosed |