Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190006 | 0.82 | MEN1 (0.36) | LMNAPDE4AMEN1KMT2ATDP1 | |
| SCHEMBL33148 | 0.80 | SMN1; SMN2 (0.52) | MAPK1SMN1; SMN2LMNAMAPTPDE4A | |
| SCHEMBL33144 | 0.80 | MAPK1 (0.52) | MAPK1SMN1; SMN2LMNAMAPTPDE4A | |
| SCHEMBL9188618 | 0.79 | LMNA (0.34) | LMNAPDE4AMEN1KMT2ATDP1 | |
| SCHEMBL3290526 | 0.79 | MAPT (0.35) | MAPK1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9197498 | 0.76 | MAPK1 (0.42) | MAPK1SMN1; SMN2LMNAMAPTPDE4A | |
| SCHEMBL13012211 | 0.75 | GAA (0.37) | HSD17B10 | |
| SCHEMBL5998835 | 0.73 | LMNA (0.41) | MAPK1SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL9199029 | 0.73 | MAPK1 (0.41) | MAPK1SMN1; SMN2LMNAMAPTPDE4A | |
| SCHEMBL2245306 | 0.72 | GAA (0.55) | MAPK1SMN1; SMN2LMNAMAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482477-B1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazines | BASF AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-5130428-A | Reacting trichloroacetamidinoguanidines with trifluoracetic acid derivatives and then with an alcohol or thiol | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0482477-A1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazines | BASF Aktiengesellschaft (DE) | 1992-04-29 | — | — | EP | disclosed |