Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.68 |
| ▸ | TUBB | P07437 | 6/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193617 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL3993248 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5812329 | 0.81 | TUBB4A (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL38665015 | 0.80 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5812513 | 0.80 | TUBB4A (0.76) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5809749 | 0.79 | TUBB4A (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5808169 | 0.79 | TUBB4A (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7130349 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5809644 | 0.78 | TUBB4A (0.80) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5807613 | 0.78 | TUBB4A (0.85) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399699-A | Lipoxygenase inihibitors, antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-03-21 | — | — | US | disclosed |