Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469481 | 0.65 | — | — | |
| SCHEMBL10430339 | 0.65 | KDM4E (0.53) | MAPTSNCAKDM4EGAARECQL | |
| SCHEMBL4362534 | 0.64 | HDAC6 (0.72) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL27828053 | 0.64 | HDAC6 (0.72) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL18346609 | 0.62 | HDAC6 (1.00) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL171446 | 0.62 | HDAC6 (1.00) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL22763952 | 0.62 | RAB9A (0.58) | L3MBTL1ALPLKDM4EGAAALPG | |
| SCHEMBL9672792 | 0.61 | HDAC6 (0.44) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL9140722 | 0.61 | HDAC6 (0.67) | HDAC6TOP1TERTMAPTSNCA | |
| SCHEMBL31472702 | 0.61 | HDAC6 (0.67) | HDAC6TOP1TERTMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416810-B1 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1995-02-08 | — | — | EP | disclosed |
| US-5275816-A | Cephalosporin derivatives | BEECHAM GROUP P.L.C. (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0416810-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | Beecham Group p.l.c. (GB) | 1991-03-13 | — | — | EP | disclosed |