Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159215 | 0.91 | MAPT (0.40) | MAPTTRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL9153352 | 0.88 | SLC7A5 (0.44) | MAPTTRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL9153390 | 0.85 | P2RY10 (0.38) | — | |
| SCHEMBL29683951 | 0.78 | TRPV1 (0.61) | MAPTTRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL2819987 | 0.78 | TRPV1 (0.61) | MAPTTRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL9151954 | 0.77 | MAPT (0.50) | MAPTMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9152905 | 0.77 | MAPT (0.35) | MAPTTRPV1MEN1KMT2AHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL9155909 | 0.75 | SMN1; SMN2 (0.45) | MAPTMEN1KMT2AHSD17B10ALOX12 | |
| SCHEMBL9155161 | 0.74 | TSHR (0.56) | MAPTMEN1KMT2AHSD17B10GAA | |
| SCHEMBL10600900 | 0.73 | ADRB2 (0.60) | MAPTMEN1KMT2AHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430336-B1 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON SPA (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5138084-A | PROCESS FOR THE PREPARATION OF 4-O-PHOSPHATES OF DOPAMINE AND DOPAMINE DERIVATIVES | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1992-08-11 | — | — | US | disclosed |
| EP-0430336-A2 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON GROUP S.p.A. (IT) | 1991-06-05 | — | — | EP | disclosed |