Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155296 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9148973 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9147469 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9150501 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9154592 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9152073 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9147371 | 0.98 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6668221 | 0.70 | LMNA (0.33) | GPR84FFAR1CA1CA2 | |
| SCHEMBL17797108 | 0.69 | LMNA (0.41) | CA2 | |
| Cyclohexane SCHEMBL28302400 | 0.67 | ACE2 (0.68) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | claimed |
| US-5472946-A | Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes | DISCOVERY THERAPEUTICS, INC. | 1995-12-05 | — | — | US | disclosed |
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | disclosed |
| US-5444075-A | Penetration enhancers for transdermal delivery of systemic agents | MINASKANIAN GEVORK (US) | 1995-08-22 | — | — | US | disclosed |
| US-5118676-A | Administering carboxylic derivatives as enhancer with systemically active agents | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118692-A | Penetration enhances for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4996199-A | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1991-02-26 | — | — | US | disclosed |