SCHEMBL9151925

SCHEMBL9151925

O=S(O)c1ccccc1-c1ccccc1S(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.44
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
CDC25B P30305 2/20 0.36
APAF1 O14727 2/20 0.36
TDP2 O95551 2/20 0.36
MAOA P21397 3/20 0.35
MAPK1 P28482 2/20 0.35
RECQL P46063 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
CES2 O00748 1/20 0.35
TERT O14746 1/20 0.35
NPC1 O15118 1/20 0.35
PLIN1 O60240 1/20 0.35
S1PR4 O95977 1/20 0.35
LMNA P02545 1/20 0.35
PLA2G1B P04054 1/20 0.35
BCHE P06276 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638619 0.89 G6PD (0.52) G6PDMEN1KMT2AAPAF1TDP2
SCHEMBL29700217 0.89 G6PD (0.52) G6PDMEN1KMT2AAPAF1TDP2
SCHEMBL10639950 0.87 ALDH1A1 (0.41) G6PDMEN1KMT2AAPAF1MAPK1
SCHEMBL4452441 0.85 ALDH1A1 (0.44) G6PDMEN1KMT2AMAPK1KDM4E
SCHEMBL23752352 0.85 ALDH1A1 (0.44) G6PDMEN1KMT2AMAPK1KDM4E
SCHEMBL9153083 0.85 G6PD (0.50) G6PDRECQLKDM4EMAPTCES2
SCHEMBL7201307 0.84 ALDH1A1 (0.43) G6PDMEN1KMT2AMAPK1KDM4E
SCHEMBL27957792 0.84 ALDH1A1 (0.43) G6PDMEN1KMT2AMAPK1KDM4E
SCHEMBL771208 0.83 BAZ2B (0.40) G6PDKMT2ACYP2C19
SCHEMBL11859134 0.82 G6PD (0.48) G6PDRECQLKDM4EMAPTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed
EP-0405389-B1 Process for producing an aromatic compound MITSUBISHI CHEM IND (JP) 1995-01-04 EP disclosed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US disclosed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP disclosed
US-4659856-A 4,4'-bis-(β-hydroxyethylsulfonyl)-biphenyl and its esters HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-21 US disclosed