SCHEMBL9152199

SCHEMBL9152199

Cc1cccc(C(CC(=O)O)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSA P10619 8/20 0.52
ACP3 P15309 1/20 0.51
BRD4 O60885 1/20 0.51
CYP26A1 O43174 1/20 0.49
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
FFAR1 O14842 1/20 0.47
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC6A9 P48067 1/20 0.45
GABBR2 O75899 1/20 0.44
GABBR1 Q9UBS5 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.43
TDP2 O95551 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27797767 0.84 CYP26A1 (0.50) CTSAACP3CYP26A1MGAMGAA
SCHEMBL9155517 0.83 CACNA2D1 (0.55) BRD4FFAR1GABBR2GABBR1LMNA
SCHEMBL29883209 0.83 CACNA2D1 (0.55) BRD4FFAR1GABBR2GABBR1LMNA
SCHEMBL8921884 0.83 ACP3 (0.49) ACP3BRD4MGAMGAASI
3,3-Diphenylpropanoic Acid SCHEMBL5283373 0.82 GABBR2 (0.59) FFAR1GABBR2GABBR1LMNAPOLB
3,3-Diphenylpropanoic Acid SCHEMBL66473 0.82 GABBR2 (0.59) FFAR1GABBR2GABBR1LMNAPOLB
SCHEMBL14609675 0.82 CYP26A1 (0.49) CTSAACP3CYP26A1FFAR1ATM
SCHEMBL9085971 0.82 FFAR1 (0.50) CTSAACP3CYP26A1MGAMGAA
SCHEMBL279936 0.82 CYP26A1 (0.49) CTSAACP3CYP26A1FFAR1ATM
3,3-Diphenylpropanoic Acid SCHEMBL8965643 0.81 BRD4 (0.51) CTSABRD4GAAFFAR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197036-B Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide 中国科学院理化技术研究所 2024-01-23 CN disclosed
CN-115197036-A Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis 中国科学院理化技术研究所 2022-10-18 CN disclosed
US-5414008-A Hypotensive and antiatherosclerotic agents BAYER AKTIENGESELLSCHAFT (DE) 1995-05-09 US disclosed
EP-0578002-A1 Imidazolyl substituted phenylpropionic and cinnamic acid derivatives BAYER AG (DE) 1994-01-12 EP disclosed