Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 7/20 | 0.45 |
| ▸ | RXRB | P28702 | 7/20 | 0.45 |
| ▸ | RXRG | P48443 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150030 | 1.00 | PPARD (0.46) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9153947 | 1.00 | PPARD (0.46) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9151359 | 1.00 | PPARD (0.46) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9152238 | 0.94 | RXRA (0.43) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9150972 | 0.94 | RXRA (0.43) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9148476 | 0.91 | RXRA (0.52) | RXRARXRBRXRGHPGDMEN1 | |
| SCHEMBL9149302 | 0.91 | RXRA (0.52) | RXRARXRBRXRGHPGDMEN1 | |
| SCHEMBL9150010 | 0.81 | RXRA (0.40) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9150003 | 0.81 | RXRA (0.40) | PPARDRXRARXRBRXRGHPGD | |
| SCHEMBL9150023 | 0.79 | PPARD (0.44) | PPARDRXRARXRBRXRGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |