Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.43 |
| ▸ | RXRB | P28702 | 6/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | C5 | P01031 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152238 | 1.00 | RXRA (0.43) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9153947 | 0.94 | PPARD (0.46) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9151359 | 0.94 | PPARD (0.46) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9150030 | 0.94 | PPARD (0.46) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9152575 | 0.94 | PPARD (0.46) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9150003 | 0.86 | RXRA (0.40) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9150010 | 0.86 | RXRA (0.40) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9146520 | 0.84 | RXRA (0.40) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9147494 | 0.84 | SIRT2 (0.55) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9148476 | 0.84 | RXRA (0.52) | RXRARXRBNR4A2RXRGAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |