Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.45 |
| ▸ | MMP3 | P08254 | 7/20 | 0.45 |
| ▸ | ACE | P12821 | 11/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151448 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9154523 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9150799 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9151119 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9151568 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9151655 | 0.99 | MMP1 (0.47) | MMP1MMP3ACEMMECCR2 | |
| SCHEMBL9147081 | 0.96 | ACE (0.45) | MMP1MMP3ACEMME | |
| SCHEMBL9150123 | 0.95 | ACE (0.47) | MMP1MMP3ACE | |
| SCHEMBL9152667 | 0.93 | ACE (0.47) | MMP1MMP3ACEMME | |
| SCHEMBL9150623 | 0.91 | ACE (0.46) | MMP1MMP3ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472946-A | Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes | DISCOVERY THERAPEUTICS, INC. | 1995-12-05 | — | — | US | disclosed |
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | disclosed |
| US-5234959-A | Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream | WHITBY RESEARCH, INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5118692-A | Penetration enhances for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4996199-A | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1991-02-26 | — | — | US | disclosed |
| WO-1989011275-A1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-11-30 | — | — | WO | disclosed |