SCHEMBL9153073

SCHEMBL9153073

CC(C)(C)c1cc(O)c(C(C)(C)C)cc1[O]

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.71
ALDH1A1 P00352 6/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
CYP1A2 P05177 2/20 0.71
MAPT P10636 2/20 0.71
KDM4E B2RXH2 1/20 0.71
ATP2A2 P16615 1/20 0.71
ATP2A3 Q93084 1/20 0.71
TP53 P04637 3/20 0.52
CYP3A4 P08684 2/20 0.52
LMNA P02545 2/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
CYP2C9 P11712 3/20 0.46
TYR P14679 2/20 0.46
HTT P42858 2/20 0.46
NR1I2 O75469 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38604 0.84 ALOX15 (1.00) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
Methane SCHEMBL28686923 0.82 ALOX15 (0.94) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL31310910 0.82 ALOX15 (0.94) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
Bicarbonate SCHEMBL11614213 0.80 ALDH1A1 (0.79) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL8609578 0.79 ALOX15 (0.88) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL7647492 0.79 ALOX15 (0.88) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL627857 0.78 ALOX15 (0.75) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL29414126 0.78 ALOX15 (0.75) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL5470246 0.78 ALOX15 (0.75) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
Methoxymethane SCHEMBL9777263 0.77 ALDH1A1 (0.83) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed