SCHEMBL915310

SCHEMBL915310

CCCCCCCCCC(C=O)[Si](OCC)(OCC)OCC.[SiH4]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
TSHR P16473 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SMPD1 P17405 3/20 0.33
MAPT P10636 2/20 0.33
OPRM1 P35372 1/20 0.33
TRPA1 O75762 1/20 0.33
DDAH1 O94760 1/20 0.33
GAPDH P04406 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
GPR84 Q9NQS5 3/20 0.32
FDPS P14324 3/20 0.32
FFAR1 O14842 1/20 0.32
TP53 P04637 1/20 0.32
LCK P06239 1/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331785 0.98 ADH1B (0.39) ADH1BADH1CADH1AADH4ADH7
SCHEMBL28676752 0.98 ADH1B (0.39) ADH1BADH1CADH1AADH4ADH7
Ethylene Glycol SCHEMBL631056 0.84 ADH1B (0.33) ADH1BADH1CADH1AADH4ADH7
SCHEMBL22638056 0.82 ADH1B (0.38) ADH1BADH1CADH1AADH4ADH7
SCHEMBL4375644 0.81 ADH1B (0.40) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3908818 0.81 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3918478 0.81 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3910839 0.81 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3913385 0.79 ADH1B (0.36) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3919931 0.79 ADH1B (0.36) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2255188-B1 BIOSENSOR FOR THE DETECTION OF NEUROTRANSMITTERS IMEC (BE) 2016-08-24 EP disclosed
US-8569006-B2 Cell-enzyme based biosensors IMEC (BE) 2013-10-29 US disclosed
US-20110003322-A1 CELL-ENZYME BASED BIOSENSORS IMEC (BE) 2011-01-06 US disclosed
EP-2255188-A1 CELL-ENZYME BASED BIOSENSORS IMEC (BE) 2010-12-01 EP disclosed
WO-2009106101-A1 CELL-ENZYME BASED BIOSENSORS INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (BE) 2009-09-03 WO disclosed