Ethylene Glycol

Ethylene Glycol

SCHEMBL631056

CCCCCCCCCC(C=O)[Si](OCC)(OCC)OCC.CCOC(C)OCC.OCCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
PSMD14 O00487 2/20 0.33
PLA2G1B P04054 2/20 0.33
MMP2 P08253 2/20 0.33
ATG4B Q9Y4P1 2/20 0.33
PTPN1 P18031 1/20 0.33
HSP90AA1 P07900 1/20 0.33
RAD52 P43351 1/20 0.33
LMNA P02545 2/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28676752 0.85 ADH1B (0.39) ADH1BADH1CADH1AADH4ADH7
SCHEMBL331785 0.85 ADH1B (0.39) ADH1BADH1CADH1AADH4ADH7
SCHEMBL915310 0.84 ADH1B (0.38) ADH1BADH1CADH1AADH4ADH7
Heptanal SCHEMBL873107 0.73 TSHR (0.55) LMNATP53
SCHEMBL22638056 0.71 ADH1B (0.38) ADH1BADH1CADH1AADH4ADH7
SCHEMBL4375644 0.71 ADH1B (0.40) ADH1BADH1CADH1AADH4ADH7
Ethylene Glycol SCHEMBL14689834 0.71 TSHR (0.61) LMNA
SCHEMBL3918478 0.70 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3908818 0.70 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7
SCHEMBL3910839 0.70 ADH1B (0.37) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10926234-B2 Catalyst composition with mixed selectivity control agent and method W. R. GRACE & CO.-CONN. (US) 2021-02-23 US disclosed
US-20190247818-A1 Catalyst Composition With Mixed Selectivity Control Agent And Method W. R. GRACE & CO.-CONN. (US) 2019-08-15 US disclosed
US-10322394-B2 Catalyst composition with mixed selectivity control agent and method W. R. GRACE & CO.-CONN. (US) 2019-06-18 US disclosed
US-10207238-B2 Catalyst composition with mixed selectivity control agent and method W. R. GRACE & CO.-CONN. (US) 2019-02-19 US disclosed
EP-2315790-B1 HIGH MELT FLOW PROPYLENE IMPACT COPOLYMER AND METHOD GRACE W R & CO (US) 2018-04-25 EP disclosed
WO-2017103053-A1 COMPOSITION COMPRISING AT LEAST ONE SULFITE WITH A PH LESS THAN 5.0 L'OREAL (FR) 2017-06-22 WO disclosed
US-9434796-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-09-06 US disclosed
US-9382342-B2 Procatalyst composition with alkoxyalkyl 2-propenoate internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-07-05 US disclosed
US-9382343-B2 Procatalyst composition with alkoxypropyl ester internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-07-05 US disclosed
US-9175026-B2 Synthesis of thioether containing trialkoxysilanes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-11-03 US disclosed
EP-2315790-A1 HIGH MELT FLOW PROPYLENE IMPACT COPOLYMER AND METHOD Dow Global Technologies LLC (US) 2011-05-04 EP disclosed
US-7893003-B2 Catalyst composition with mixed selectivity control agent and method DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-22 US disclosed
WO-2010123775-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-28 WO disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 US disclosed
WO-2010120973-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 WO disclosed
WO-2010082943-A1 HIGH MELT FLOW PROPYLENE IMPACT COPOLYMER AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-22 WO disclosed
WO-2010021762-A1 CATALYST COMPOSITION WITH MIXED SELECTIVITY CONTROL AGENT AND POLYMERISATION METHOD USING IT DOW GLOBAL TECHNOLOGIES INC. (US) 2010-02-25 WO disclosed
US-20090209706-A1 High Melt Flow Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2009-08-20 US disclosed
US-20090203863-A1 Catalyst Composition with Mixed Selectivity Control Agent and Method W. R. GRACE & CO.-CONN. 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method MPST, TST, TKT ADH1B 637/4885ADH1C 1665/4885ADH1A 577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.