Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 7/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148428 | 0.90 | OXER1 (0.46) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9153196 | 0.88 | OXER1 (0.47) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9156276 | 0.87 | OXER1 (0.48) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9149130 | 0.86 | OXER1 (0.41) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9150612 | 0.85 | OXER1 (0.48) | AKR1C3AKR1C2AKR1C4PTGS1HTR6 | |
| SCHEMBL9149623 | 0.84 | OXER1 (0.46) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9153111 | 0.83 | SRD5A1 (0.55) | PLA2G4AAKR1C3AKR1C2AKR1C4PTGS1 | |
| SCHEMBL9429193 | 0.82 | OXER1 (0.47) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9538976 | 0.80 | PPARD (0.41) | PLA2G4AAKR1C3AKR1C2AKR1C4PTGS1 | |
| SCHEMBL9152733 | 0.80 | AKR1C3 (0.42) | AKR1C3AKR1C2AKR1C4PTGS1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |