Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 7/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153385 | 0.84 | LMNA (0.54) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL9766033 | 0.84 | LMNA (0.51) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL17969124 | 0.81 | ALDH1A1 (0.54) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL11284893 | 0.80 | LMNA (0.48) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL31379038 | 0.80 | LMNA (0.60) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL29062859 | 0.80 | LMNA (0.60) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL25789187 | 0.80 | BRD4 (0.57) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL29960617 | 0.80 | ALDH1A1 (0.53) | LMNAALDH1A1CREBBPBRD4EP300 | |
| Hydrochloric Acid SCHEMBL29960669 | 0.79 | ALDH1A1 (0.51) | LMNAALDH1A1CREBBPBRD4EP300 | |
| SCHEMBL28558501 | 0.77 | LMNA (0.54) | LMNAALDH1A1CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |