SCHEMBL9153268

SCHEMBL9153268

O=S(=O)(O)c1ccc(Oc2cc[c]cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 10/20 0.47
LMNA P02545 8/20 0.47
ALDH1A1 P00352 7/20 0.47
HTT P42858 7/20 0.47
TSHR P16473 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
XBP1 P17861 1/20 0.47
MAPK1 P28482 1/20 0.47
MDM2 Q00987 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NT5E P21589 1/20 0.43
POLB P06746 2/20 0.42
SOS1 Q07889 2/20 0.41
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6090901 0.87 ALDH1A1 (0.58) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL9249636 0.87 ALDH1A1 (0.58) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL28521152 0.85 ALDH1A1 (0.56) SMN1; SMN2LMNAALDH1A1HTTTSHR
Water SCHEMBL28012117 0.80 TSHR (0.55) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL50583 0.80 TSHR (0.55) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL2937729 0.80 HTT (0.47) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL1133806 0.79 SOS1 (0.64) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL4833872 0.78 TSHR (0.52) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL2174084 0.78 TSHR (0.52) SMN1; SMN2LMNAALDH1A1HTTTSHR
SCHEMBL27579780 0.78 TSHR (0.52) SMN1; SMN2LMNAALDH1A1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1727998-A Photosensitive acid generator containing fluorine ether type structure and multiple functional groups and preparation method thereof HUATAI CHEMICAL CO LTD CHANGZH (CN) 2006-02-01 CN disclosed
CN-1105114-C Sulfonyl divalent aryl alpha-hydroxamic acid compounds MANSANTO CO (US) 2003-04-09 CN disclosed
CN-1360577-A Hydroxamic acid derivs. as matrix metalloprotease inhibitors SEARLE & CO (US) 2002-07-24 CN disclosed
CN-1254337-A N-hydroxy 4-sulfonylbutyramide compounds MONSANTO CO (US) 2000-05-24 CN disclosed
CN-1253559-A Sulfonyl divalent aryl alpha-hydroxamic acid compounds MONSANTO CO (US) 2000-05-17 CN disclosed
CN-1253474-A Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds MONSANTO CO (US) 2000-05-17 CN disclosed
CN-1230884-A Thiol sulfone metalloprotease inhibitors MONSANTO CO (US) 1999-10-06 CN disclosed
EP-0258903-B1 Silver halide photographic light-sensitive material having a reflective base KONISHIROKU PHOTO IND (JP) 1995-01-11 EP disclosed
EP-0350923-B1 A METHOD AND A SOLUTION FOR PROCESSING PHOTOSENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS KONICA CORPORATION (JP) 1993-09-15 EP disclosed
EP-0269227-B1 METHOD FOR COMMON DEVELOPMENT PROCESSING OF TWO KINDS OF LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-12-30 EP disclosed
EP-0269227-A2 Method for common development processing of two kinds of light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1988-06-01 EP disclosed
US-4746598-A SUPPRESSION OF STAINING IN UNEXPOSED PORTIONS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-05-24 US disclosed
EP-0258903-A2 Silver halide photographic light-sensitive material having a reflective base KONICA CORPORATION (JP) 1988-03-09 EP disclosed
EP-0199604-A2 Processing method for light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-10-29 EP disclosed
EP-0189191-A2 Processing method of silver halide color photosensitive material KONICA CORPORATION (JP) 1986-07-30 EP disclosed
EP-0186169-A2 Method for processing of light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-07-02 EP disclosed
EP-0186504-A2 Processing method of silver halide color photosensitive material KONICA CORPORATION (JP) 1986-07-02 EP disclosed
EP-0185371-A2 Method of processing light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-06-25 EP disclosed
US-4587195-A TWO TRIAZYLSTIBLENE BRIGHTENING AGENTS ADDED TO SENSITIZING AND ANTIIRRADIATION DYES TO PREVENT COLOR STAIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-05-06 US disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed