Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547843 | 0.87 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL8941654 | 0.81 | PTGS2 (0.56) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL20194 | 0.80 | ENPP2 (0.50) | PTGS2ENPP2 | |
| SCHEMBL9153268 | 0.80 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL13814624 | 0.79 | HTT (0.63) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL7359540 | 0.79 | SOS1 (0.64) | HTTSMN1; SMN2LMNAPTGS2TSHR | |
| SCHEMBL8005674 | 0.79 | PKM (0.61) | PTGS2NPC1RAB9APTGS1 | |
| SCHEMBL2758531 | 0.79 | HTT (0.63) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL2894725 | 0.78 | PTGS2 (0.38) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL3913682 | 0.78 | HTT (0.48) | HTTSMN1; SMN2LMNAALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |
| CN-100457823-C | Epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained thereof | MITSUI CHEMICALS INC (JP) | 2009-02-04 | — | — | CN | disclosed |
| CN-1285636-C | Process for producing oxyalkylene derivative | MITSUI CHEMICALS INC (JP) | 2006-11-22 | — | — | CN | disclosed |
| CN-1781985-A | Epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained thereof | MITSUI CHEMICALS INC (JP) | 2006-06-07 | — | — | CN | disclosed |
| CN-1592764-A | Method for producing organic compound, epoxy resin composition, cured product of the epoxy resin, and semiconductor device formed using the epoxy resin | MITSUI CHEMICALS INC (JP) | 2005-03-09 | — | — | CN | disclosed |